Wednesday, 3 October 2012

magnesium citrate


Generic Name: magnesium citrate (mag NEE see um SIH trate)

Brand names: Citrate of Magnesia, Citroma, Citroma Cherry, Citroma Lemon


What is magnesium citrate?

Magnesium is a naturally occurring mineral. Magnesium is important for many systems in the body especially the muscles and nerves. Magnesium citrate also increases water in the intestines, which may induce defecation.


Magnesium hydroxide is used as a laxative to relieve occasional constipation (irregularity).


Magnesium citrate may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about magnesium citrate?


Before taking magnesium citrate, tell your doctor if you have any other medical conditions, allergies, or if you take other medicines or other herbal/health supplements. Magnesium citrate may not be recommended in some situations.


Do not use magnesium citrate as a laxative if you have stomach (abdominal) pain, nausea, or vomiting, unless directed by a doctor. If you notice a sudden change in bowel habits that persists over a period of 2 weeks, consult your healthcare provider before using a laxative. Magnesium citrate should not be used for longer than one week, unless otherwise directed by your healthcare provider. Rectal bleeding or failure to have a bowel movement after use of a laxative may indicate a more serious condition; stop using magnesium citrate and contact your healthcare provider.

What should I discuss with my healthcare provider before taking magnesium citrate?


Do not take magnesium citrate without first talking to your doctor if you have kidney disease. Do not use magnesium citrate as a laxative if you have stomach (abdominal) pain, nausea, or vomiting, unless directed by a doctor. If you notice a sudden change in bowel habits that persists over a period of 2 weeks, consult your healthcare provider before using a laxative. Magnesium citrate should not be used for longer than one week, unless otherwise directed by your healthcare provider. Rectal bleeding or failure to have a bowel movement after use of a laxative may indicate a more serious condition; stop using magnesium citrate and contact your healthcare provider.

Before taking magnesium citrate, tell your doctor if you have any other medical conditions, allergies, or if you take other medicines or other herbal/health supplements. Magnesium citrate may not be recommended in some situations.


It is not known whether magnesium citrate will be harmful to an unborn baby. Do not take magnesium citrate without first talking to your doctor if you are pregnant or planning a pregnancy. It is not known whether magnesium citrate will be harmful to an nursing baby. Do not take magnesium citrate without first talking to your doctor if you are breast-feeding a baby.

How should I take magnesium citrate?


Take magnesium citrate exactly as directed by your doctor or as directed on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.


For best results, take magnesium citrate on an empty stomach followed by a full glass of water. Chilling the medication in the refrigerator or giving it with ice may improve the taste.

To ensure that you get the correct dose, measure the liquid form of magnesium with a dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.


Do not use magnesium citrate as a laxative if you have stomach (abdominal) pain, nausea, or vomiting, unless directed by a doctor. If you notice a sudden change in bowel habits that persists over a period of 2 weeks, consult your healthcare provider before using a laxative. Magnesium citrate should not be used for longer than one week, unless otherwise directed by your healthcare provider. Rectal bleeding or failure to have a bowel movement after use of a laxative may indicate a more serious condition; stop using magnesium citrate and contact your healthcare provider. Do not take more magnesium citrate than is directed. Store magnesium citrate at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication.


What happens if I overdose?


Seek emergency medical attention.

Symptoms of an magnesium citrate overdose include nausea, vomiting, flushing, low blood pressure, a slow heartbeat, drowsiness, coma, and death.


What should I avoid while taking magnesium citrate?


There are no restrictions on food, beverages, or activity while taking magnesium citrate unless otherwise directed by your doctor.


Magnesium citrate side effects


Stop taking magnesium citrate and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take magnesium citrate and talk to your doctor if you experience diarrhea, upset stomach, dizziness, or sweating.


Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


Magnesium citrate Dosing Information


Usual Adult Dose for Constipation:

240 mL orally one time.

Usual Pediatric Dose for Constipation:


6 to 12 years: 100 to 150 mL orally one time.


What other drugs will affect magnesium citrate?


Before taking magnesium citrate, talk to your doctor if you are taking



  • a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others);




  • a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), enoxacin (Penetrex), norfloxacin (Noroxin), sparfloxacin (Zagam), levofloxacin (Levaquin), lomefloxacin (Maxaquin), grepafloxacin (Raxar), and others;




  • penicillamine (Cuprimine);




  • digoxin (Lanoxin, Lanoxicaps); or




  • nitrofurantoin (Macrodantin, Furadantin, others).



You not be able to take magnesium citrate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.


Drugs other than those listed here can also interact with magnesium citrate. Talk to your doctor and pharmacist before taking any over-the-counter or prescription medicines, including herbal products.



More magnesium citrate resources


  • Magnesium citrate Side Effects (in more detail)
  • Magnesium citrate Use in Pregnancy & Breastfeeding
  • Magnesium citrate Drug Interactions
  • Magnesium citrate Support Group
  • 4 Reviews for Magnesium citrate - Add your own review/rating


  • Magnesium Citrate Solution MedFacts Consumer Leaflet (Wolters Kluwer)

  • Magnesium Citrate Professional Patient Advice (Wolters Kluwer)

  • Citrate Of Magnesia Advanced Consumer (Micromedex) - Includes Dosage Information



Compare magnesium citrate with other medications


  • Constipation


Where can I get more information?


  • Your pharmacist has additional information about magnesium citrate written for health professionals that you may read.

See also: magnesium citrate side effects (in more detail)


Monday, 1 October 2012

Muro-128


Generic Name: sodium chloride (Ophthalmic route)


SOE-dee-um KLOR-ide


Commonly used brand name(s)

In the U.S.


  • AK-NaCl

  • Muro-128

  • OcuFresh

  • Sochlor

In Canada


  • Cordema

  • Eye Wash

  • In A Wink Daily Cleaner

  • In A Wink Neutralizing Rinse

Available Dosage Forms:


  • Solution

  • Ointment

Therapeutic Class: Osmotherapy Agent


Uses For Muro-128


Hypertonic sodium chloride solution for the eye is used to draw water out of a swollen cornea. The extra water in the cornea can cause your vision to be poor. You may also see halos or rings around point light sources. The cornea is the clear cover over the colored part of your eye.



Before Using Muro-128


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Although there is no specific information comparing use of hypertonic sodium chloride in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of hypertonic sodium chloride in the elderly with use in other age groups.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Proper Use of sodium chloride

This section provides information on the proper use of a number of products that contain sodium chloride. It may not be specific to Muro-128. Please read with care.


To use:


  • The bottle is only partially full to provide proper drop control.

  • First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed.

  • If you think you did not get the drop of medicine into your eye properly, use another drop.

  • Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.

  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. Serious damage to the eye and possible loss of vision may result from using contaminated eye drops.

Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For ophthalmic solution (eye drops) dosage form:
    • For swelling of the cornea:
      • Adults—Use 1 drop every three or four hours.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Muro-128


Use only under the advice and supervision of a doctor.


If you experience eye pain, changes in vision, continued redness or irritation of the eye, or if your symptoms continue for more than 3 days or become worse, check with your doctor.


Importance of not contaminating the product. Do not touch the tip of the container to the eye or any surface.


Do not use if the solution changes color or becomes cloudy.


Replace cap after each use. Store container upright.


Muro-128 Side Effects


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More Common
  • temporary burning sensation of the eye

  • temporary eye irritation

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Muro-128 resources


  • Muro-128 Support Group
  • 0 Reviews · Be the first to review/rate this drug

methazolamide


Generic Name: methazolamide (meth a ZOLE a mide)

Brand Names: Glauctabs, MZM, Neptazane


What is methazolamide?

Methazolamide is a carbonic anhydrase inhibitor. Carbonic anhydrase is a protein in the body. Methazolamide reduces the activity of this protein.


Methazolamide is used to treat glaucoma. By inhibiting the actions of carbonic anhydrase, methazolamide reduces the amount of fluid produced in the eyes and therefore also reduces pressure.


Methazolamide may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about methazolamide?


Contact your doctor immediately if you experience a sore throat, fever, unusual bleeding or bruising, tingling or tremors in the hands or feet, pain in the side or groin, or a rash. These symptoms could be early signs of a serious side effect.


Use caution when driving, operating machinery, or performing other hazardous activities. Methazolamide may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Avoid prolonged exposure to sunlight. Methazolamide may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

What should I discuss with my healthcare provider before taking methazolamide?


Tell your doctor if you have ever had an allergic reaction to a sulfa-based drug such as sulfamethoxazole (e.g., Bactrim, Septra, Gantanol). Methazolamide is also a sulfa-based drug, and you may have a similar reaction to it.


Before taking methazolamide, tell your doctor if you



  • are on aspirin therapy,




  • have liver disease,




  • have kidney disease,




  • have heart disease,




  • have lung disease, or




  • have a hormonal disease.



You may not be able to take methazolamide, or you may require a dosage adjustment special monitoring during treatment if you have any of the conditions listed above.


Methazolamide is in the FDA pregnancy category C. This means that it is not known whether methazolamide will be harm an unborn baby. Do not take methazolamide without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether methazolamide passes into breast . Do not take methazolamide without first talking to your doctor if you are breast-feeding a baby.

How should I take methazolamide?


Take methazolamide exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.


Take each dose with a full glass of water. Take methazolamide with food if it causes stomach upset.

It is important to take methazolamide regularly to get the most benefit.


Store methazolamide at room temperature away from moisture and heat.

See also: Methazolamide dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.


What happens if I overdose?


Seek emergency medical attention if an overdose is suspected.

Symptoms of a methazolamide overdose include drowsiness, decreased appetite, nausea, vomiting, dizziness, numbness or tingling, shaking, and ringing in the ears.


What should I avoid while taking methazolamide?


Use caution when driving, operating machinery, or performing other hazardous activities. Methazolamide may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Avoid prolonged exposure to sunlight. Methazolamide may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Methazolamide side effects


If you experience any of the following serious side effects, stop taking methazolamide and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);




  • a sore throat or a fever;




  • unusual bleeding or bruising;




  • side or groin pain;




  • tingling or tremors in the hands or feet; or




  • a rash.



Other, less serious side effects may be more likely to occur. Continue to take methazolamide and talk to your doctor if you experience



  • decreased appetite, nausea, vomiting, constipation, diarrhea, or changes in taste;




  • drowsiness, dizziness, fatigue, or weakness;




  • nervousness or tremor;




  • headache or confusion;




  • increased sensitivity of the skin to sunlight;




  • worsening gout;




  • loss of blood sugar control (if you are diabetic);




  • ringing in your ears or hearing problems; or




  • changes in vision.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


Methazolamide Dosing Information


Usual Adult Dose for Glaucoma:

Open-angle glaucoma: 50 to 100 mg orally 2 to 3 times daily

Secondary glaucoma: 50 to 100 mg orally 2 to 3 times daily

Acute angle-closure glaucoma (preoperatively only): 50 to 100 mg 2 to 3 times daily


What other drugs will affect methazolamide?


Before taking this medication, tell your doctor if you are taking any of the following medicines:



  • cyclosporine (Sandimmune);




  • primidone (Mysoline);




  • diflunisal (Dolobid;




  • aspirin, salsalate (Disalcid, Salflex, Salsitab, others), choline salicylate (Arthropan), magnesium salicylate (Doan's, Magan, Mobidin), or other aspirin-like products (salicylates); or




  • lithium (Lithobid, Eskalith, others).



You may not be able to take methazolamide, or you may require a dosage adjustment or special monitoring during treatment.


Drugs other than those listed here may also interact with methazolamide. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.



More methazolamide resources


  • Methazolamide Side Effects (in more detail)
  • Methazolamide Dosage
  • Methazolamide Use in Pregnancy & Breastfeeding
  • Drug Images
  • Methazolamide Drug Interactions
  • Methazolamide Support Group
  • 0 Reviews for Methazolamide - Add your own review/rating


  • Methazolamide Prescribing Information (FDA)

  • Methazolamide MedFacts Consumer Leaflet (Wolters Kluwer)

  • Methazolamide Professional Patient Advice (Wolters Kluwer)

  • Methazolamide Monograph (AHFS DI)

  • Neptazane Prescribing Information (FDA)



Compare methazolamide with other medications


  • Glaucoma


Where can I get more information?


  • Your pharmacist has more information about methazolamide written for health professionals that you may read.

See also: methazolamide side effects (in more detail)