Nicotine Drug Facts

Dosage Form: lozenge
Drug Facts

Active ingredient (in each lozenge)

Nicotine polacrilex, 4 mg

Nicotine polacrilex, 2 mg

Purpose

Stop smoking aid

Uses

reduces withdrawal symptoms, including nicotine craving, associated with quitting smoking

Warnings

If you are pregnant or breast-feeding, only use this medicine on the advice of your health care provider. Smoking can seriously harm your child. Try to stop smoking without using any nicotine replacement medicine. This medicine is believed to be safer than smoking. However, the risks to your child from this medicine are not fully known.

Do not use

• if you continue to smoke, chew tobacco, use snuff, or use a nicotine patch or other nicotine containing product

Ask a doctor before use if you have

• a sodium-restricted diet


• heart disease, recent heart attack, or irregular heartbeat. Nicotine can increase your heart rate.


• high blood pressure not controlled with medication. Nicotine can increase your blood pressure.


• stomach ulcer or diabetes

Ask a doctor or pharmacist before use if you are

• using a non-nicotine stop smoking drug


• taking prescription medicine for depression or asthma. Your prescription dose may need to be adjusted.

Stop use and ask a doctor if

• mouth problems occur


• persistent indigestion or severe sore throat occurs


• irregular heartbeat or palpitations occur


• you get symptoms of nicotine overdose such as nausea, vomiting, dizziness, diarrhea, weakness and rapid heartbeat

Keep out of reach of children and pets.

Nicotine lozenges may have enough nicotine to make children and pets sick. If you need to remove the lozenge, wrap it in paper and throw away in the trash. In case of overdose, get medical help or contact a Poison Control Center right away.

Directions 4mg Lozenge

• if you are under 18 years of age, ask a doctor before use


• before using this product, read the enclosed User’s Guide for complete directions and other important information


• stop smoking completely when you begin using the lozenge


• if you smoke your first cigarette more than 30 minutes after waking up, use 2mg nicotine lozenge


• if you smoke your first cigarette within 30 minutes of waking up, use 4mg nicotine lozenge according to the following 12 week schedule:


• 
  
  
  
  
  
  
  
  

  Weeks 1 to 6	Weeks 7 to 9	Weeks 10 to 12
  1 lozenge every 1 to 2 hours	1 lozenge every 2 to 4 hours	1 lozenge every 4 to 8 hours



• nicotine lozenge is a medicine and must be used a certain way to get the best results


• place the lozenge in your mouth and allow the lozenge to slowly dissolve (about 20 – 30 minutes). Minimize swallowing. Do not chew or swallow lozenge.


• you may feel a warm or tingling sensation


• occasionally move the lozenge from one side of your mouth to the other until completely dissolved (about 20 – 30 minutes)


• do not eat or drink 15 minutes before using or while the lozenge is in your mouth


• to improve your chances of quitting, use at least 9 lozenges per day for the first 6 weeks


• do not use more than one lozenge at a time or continuously use one lozenge after another since this may cause you hiccups, heartburn, nausea or other side effects


• do not use more than 5 lozenges in 6 hours. Do not use more than 20 lozenges per day.


• stop using the nicotine lozenge at the end of 12 weeks. If you still feel the need to use nicotine lozenges, talk to your doctor.

Directions 2mg Lozenge

• if you are under 18 years of age, ask a doctor before use


• before using this product, read the enclosed User’s Guide for complete directions and other important information


• stop smoking completely when you begin using the lozenge


• if you smoke your first cigarette within 30 minutes of waking up, use 4mg nicotine lozenge


• if you smoke your first cigarette more than 30 minutes after waking up, use 2mg nicotine lozenge according to the following 12 week schedule:


• 
  
  
  
  
  
  
  
  

  Weeks 1 to 6	Weeks 7 to 9	Weeks 10 to 12
  1 lozenge every 1 to 2 hours	1 lozenge every 2 to 4 hours	1 lozenge every 4 to 8 hours



• nicotine lozenge is a medicine and must be used a certain way to get the best results


• place the lozenge in your mouth and allow the lozenge to slowly dissolve (about 20 – 30 minutes). Minimize swallowing. Do not chew or swallow lozenge.


• you may feel a warm or tingling sensation


• occasionally move the lozenge from one side of your mouth to the other until completely dissolved (about 20 – 30 minutes)


• do not eat or drink 15 minutes before using or while the lozenge is in your mouth


• to improve your chances of quitting, use at least 9 lozenges per day for the first 6 weeks


• do not use more than one lozenge at a time or continuously use one lozenge after another since this may cause you hiccups, heartburn, nausea or other side effects


• do not use more than 5 lozenges in 6 hours. Do not use more than 20 lozenges per day.


• stop using the nicotine lozenge at the end of 12 weeks. If you still feel the need to use nicotine lozenges, talk to your doctor.

Other information

• Each lozenge contains: sodium, 18 mg


• Phenylketonurics: Contains Phenylalanine 3.4 mg per lozenge


• store at 20 – 25oC (68 – 77oF)


• protect from light

Inactive ingredients

aspartame, calcium polycarbophil, flavor, magnesium stearate, mannitol, potassium bicarbonate, sodium alginate, sodium carbonate, xanthan gum

Questions or comments?

call toll-free 1-877-306-0019 (English/Spanish) weekdays (9:00 am – 4:30 pm ET)

Distributed by:

Walgreen Co.,

200 Wilmot Rd., Deerfield, IL 60015-4616

Quality Guaranteed 100% Satisfaction Guaranteed with all Walgreens Products or Your Money Back.

www.walgreens.com

Compare to Commit®* Lozenge

Principal Display Panel

Nicotine Lozenge

Nicotine Polacrilex Lozenge, 4mg

STOP SMOKING AID

72 LOZENGES

4mg EACH

Includes User’s Guide

MINT FLAVOR

FOR THOSE WHO SMOKE THEIR FIRST CIGARETTE WITHIN 30 MINUTES OF WAKING UP.

If you smoke your first cigarette MORE THAN 30 MINUTES after waking up, use Nicotine Polacrilex Lozenge, 2mg

• not for sale to those under 18 years of age


• proof of age required


• not for sale in vending machines or from any source where proof of age cannot be verified

This product is protected in sealed blisters.

Do not use if individual blisters or printed backings are broken, open or torn.

TO INCREASE YOUR SUCCESS IN QUITTING:

1. You must be motivated to quit.


2. Use Enough – Use at least 9 lozenges per day during the first six weeks.


3. Use Long Enough – Use for the full 12 weeks.


4. Use With a Support Program as directed in the enclosed User’s Guide.

To remove the lozenge, tear off single unit.

Peel off backing starting at corner with loose edge.

Push lozenge through foil.

Comments/questions:

GCSP 5.4376.4C Re: Consumer Relations, PO Box 13398, Research Triangle Park, NC 27709-9627

30822XA

©2009

Principal Display Panel

Nicotine Lozenge

Nicotine Polacrilex Lozenge, 2mg

STOP SMOKING AID

72 LOZENGES

2mg EACH

Includes User’s Guide

MINT FLAVOR

FOR THOSE WHO SMOKE THEIR FIRST CIGARETTE MORE THAN 30 MINUTES AFTER WAKING UP.

If you smoke your first cigarette WITHIN 30 MINUTES of waking up, use Nicotine Polacrilex Lozenge, 4mg

• not for sale to those under 18 years of age


• proof of age required


• not for sale in vending machines or from any source where proof of age cannot be verified

This product is protected in sealed blisters.

Do not use if individual blisters or printed backings are broken, open or torn.

TO INCREASE YOUR SUCCESS IN QUITTING:

1. You must be motivated to quit.


2. Use Enough – Use at least 9 lozenges per day during the first six weeks.


3. Use Long Enough – Use for the full 12 weeks.


4. Use With a Support Program as directed in the enclosed User’s Guide.

To remove the lozenge, tear off single unit.

Peel off backing starting at corner with loose edge.

Push lozenge through foil.

Comments/questions:

GCSP 5.4376.4C Re: Consumer Relations, PO Box 13398, Research Triangle Park, NC 27709-9627

30821XA

© 2009

NICOTINE  nicotine  lozenge

Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 0363-0208 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength NICOTINE (NICOTINE) NICOTINE 2 mg

Inactive Ingredients Ingredient Name Strength POLACRILIN   ASPARTAME   CALCIUM POLYCARBOPHIL   MAGNESIUM STEARATE   MANNITOL   POTASSIUM BICARBONATE   SODIUM ALGINATE   SODIUM CARBONATE   XANTHAN GUM

Product Characteristics Color WHITE (white to off-white) Score no score Shape ROUND Size 16mm Flavor MINT Imprint Code PL2 Contains

Packaging # NDC Package Description Multilevel Packaging 1 0363-0208-01 72 LOZENGE In 1 CONTAINER None 2 0363-0208-07 108 LOZENGE In 1 CONTAINER None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
NDA	NDA021330	10/31/2002

NICOTINE  nicotine  lozenge

Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 0363-0209 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength NICOTINE (NICOTINE) NICOTINE 4 mg

Inactive Ingredients Ingredient Name Strength POLACRILIN   ASPARTAME   CALCIUM POLYCARBOPHIL   MAGNESIUM STEARATE   MANNITOL   POTASSIUM BICARBONATE   SODIUM ALGINATE   SODIUM CARBONATE   XANTHAN GUM

Product Characteristics Color WHITE (white to off-white) Score no score Shape ROUND Size 16mm Flavor MINT Imprint Code PL4 Contains

Packaging # NDC Package Description Multilevel Packaging 1 0363-0209-01 72 LOZENGE In 1 CONTAINER None 2 0363-0209-07 108 LOZENGE In 1 CONTAINER None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
NDA	NDA021330	10/31/2002

Labeler - Walgreens (008965063)

Revised: 09/2010Walgreens

More Nicotine Drug Facts resources

• Nicotine Drug Facts Side Effects (in more detail)
• Nicotine Drug Facts Use in Pregnancy & Breastfeeding
• Nicotine Drug Facts Drug Interactions
• Nicotine Drug Facts Support Group
• 42 Reviews for Nicotine Drug Facts - Add your own review/rating

Compare Nicotine Drug Facts with other medications

• Smoking Cessation

Questran Powder

Pronunciation: koe-LES-teer-a-meen
Generic Name: Cholestyramine
Brand Name: Examples include Prevalite and Questran

Questran Powder is used for:

Lowering blood cholesterol levels. It is used along with changes in diet. It is used to relieve itching caused by partial biliary obstruction. It may also be used for other conditions as determined by your doctor.

Questran Powder is a bile acid sequestrant/anion-exchange resin. It works by increasing the removal of bile acids from the body. As the body loses bile acids, it replaces them by converting cholesterol from the blood to bile acids. This causes the blood level of cholesterol to decrease.

Do NOT use Questran Powder if:

• you are allergic to any ingredient in Questran Powder


• you have a complete obstruction of your biliary tract, severe constipation (eg, impacted feces), high blood chloride levels, or certain types of elevated blood lipid levels (type III, IV, or V hyperlipidemia)


• if you are taking mycophenolate

Contact your doctor or health care provider right away if any of these apply to you.

Before using Questran Powder:

Some medical conditions may interact with Questran Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have heart disease; constipation; hemorrhoids; gallbladder problems; blood, bleeding, or clotting problems; high blood levels of triglycerides; poor absorption from the intestinal tract or other intestinal problems; kidney problems; or phenylketonuria (PKU)


• if you are dehydrated

Some MEDICINES MAY INTERACT with Questran Powder. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin), beta-blockers (eg, propranolol), digoxin, digitoxin, estrogens, hormonal contraceptives (eg, birth control pills), mycophenolate, penicillins (eg, amoxicillin), phenobarbital, phenylbutazone, phosphate supplements, progestins (eg, medroxyprogesterone), tetracyclines (eg, doxycycline), thiazide diuretics (eg, hydrochlorothiazide), or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Questran Powder


• Spironolactone because the risk of high blood chloride levels may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Questran Powder may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Questran Powder:

Use Questran Powder as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Questran Powder is usually taken by mouth with meals.


• Questran Powder may decrease the absorption of other medicines. All other medicines should be taken at least 1 hour before or 4 hours after taking Questran Powder. Check with your doctor if you have any questions about taking your other medicines along with Questran Powder.


• If you are also taking anticoagulants (eg, warfarin), take Questran Powder at least 6 hours after you take the anticoagulant unless directed otherwise by your doctor.


• Do not take Questran Powder in its dry form. Always mix with water or other fluids before taking.


• If you are taking Questran Powder with a beverage, add the prescribed amount of medicine to 2 to 6 ounces/60 to 180 mL of water or other noncarbonated liquid before taking. Stir until well mixed (it will not dissolve) before drinking. After drinking all the liquid, rinse the glass with more liquid and drink it to ensure that all medicine is received.


• Questran Powder may also be mixed with soups (chicken noodle, tomato) or fruits (eg, applesauce, crushed pineapple) containing plenty of fluid.


• Do not sip Questran Powder or hold it in your mouth for a long period of time because this may cause tooth changes such as discoloration, decay, or erosion of enamel. Maintain good oral hygiene while you are using Questran Powder.


• Drink several glasses (8 ounces/240 mL) of water or other liquid daily, unless directed otherwise by your doctor.


• If you miss a dose of Questran Powder, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Questran Powder.

Important safety information:

• Questran Powder may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Questran Powder with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• If you experience constipation while taking Questran Powder, talk to your doctor about increased fiber intake and use of a stool softener to help relieve this side effect.


• Phenylketonuria patients - Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.


• The color of the powder may vary from batch to batch. This is normal and does not change the effect.


• Hormonal birth control (eg, birth control pills) may not work as well while you are using Questran Powder. To prevent pregnancy, use an extra form of birth control (eg, condoms).


• Lab tests, including lipid and cholesterol levels and prothrombin times, may be performed while you use Questran Powder. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Questran Powder with caution in the ELDERLY; they may be more sensitive to its effects, especially constipation.


• Caution is advised when using Questran Powder in CHILDREN; they may be more sensitive to its effects, especially high blood chloride levels.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Questran Powder while you are pregnant. It is not known if Questran Powder is found in breast milk. If you are or will be breast-feeding while you use Questran Powder, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Questran Powder:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; irritation of the skin, tongue, or anal area; severe constipation; severe or persistent nausea; shortness of breath; stomach pain; unusual bruising or bleeding; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Questran side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include constipation; feeling of fullness.

Proper storage of Questran Powder:

Store Questran Powder at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Questran Powder out of the reach of children and away from pets.

General information:

• If you have any questions about Questran Powder, please talk with your doctor, pharmacist, or other health care provider.


• Questran Powder is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Questran Powder. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Questran resources

• Questran Side Effects (in more detail)
• Questran Use in Pregnancy & Breastfeeding
• Questran Drug Interactions
• Questran Support Group
• 0 Reviews for Questran - Add your own review/rating

Compare Questran with other medications

• Crohn's Disease
• Hyperlipoproteinemia
• Hyperlipoproteinemia Type IIa, Elevated LDL
• Hyperlipoproteinemia Type IIb, Elevated LDL VLDL
• Irritable Bowel Syndrome
• Pruritus of Partial Biliary Obstruction

Icopent

Icopent may be available in the countries listed below.

Ingredient matches for Icopent

Icosapent

Icosapent ethyl ester (a derivative of Icosapent) is reported as an ingredient of Icopent in the following countries:

• Japan

International Drug Name Search

Tyvaso

Generic Name: treprostinil inhalation (tre PROS ti nil)

Brand Names: Tyvaso, Tyvaso Refill Kit, Tyvaso Starter Kit

What is treprostinil inhalation?

Treprostinil works by dilating (widening) blood vessels in your lungs and by keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots. These effects lower blood pressure in the pulmonary artery that leads from your heart to your lungs.

Treprostinil is used to treat pulmonary arterial hypertension (PAH). It improves your ability to exercise and prevents your condition from getting worse.

Treprostinil may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about treprostinil inhalation?

Before using this medication, tell your doctor if you have a breathing disorder such as asthma or COPD (chronic obstructive pulmonary disease), an infection in your lungs (including pneumonia), low blood pressure, liver or kidney disease, or a bleeding or blood clotting disorder.

Treprostinil inhalation should be used only with a Tyvaso inhalation system. The inhalation system comes with patient instructions for safe and effective use. Do not use the medication at home if you do not fully understand how to use the inhalation system and properly clean it daily. Ask your doctor or pharmacist if you have any questions.

The effects of treprostinil inhalation will lessen over time between doses. Talk with your doctor if you need to time your dosing around any planned activities.

It is important to use treprostinil regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. Make sure you have a backup inhalation system available so as not to interrupt your treatment if one system stops working.

Call your doctor if your symptoms do not improve or if they get worse.

What should I discuss with my healthcare provider before using treprostinil inhalation?

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication:

• 
  

  a breathing disorder such as asthma or COPD (chronic obstructive pulmonary disease);

  
  


• 
  

  an infection in your lungs, including pneumonia;

  
  


• 
  

  low blood pressure;

  
  


• liver disease;


• kidney disease; or


• 
  

  a bleeding or blood clotting disorder.

  
  

FDA pregnancy category B. It is not known whether this medication is harmful to an unborn baby. Use an effective form of birth control while you are using treprostinil inhalation. Tell your doctor if you become pregnant during treatment. It is not known whether treprostinil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is treprostinil inhalation given?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

Treprostinil inhalation should be used only with a Tyvaso inhalation system. The inhalation system comes with patient instructions for safe and effective use. Do not use the medication at home if you do not fully understand how to use the inhalation system and properly clean it daily. Ask your doctor or pharmacist if you have any questions.

The inhalation form of treprostinil is usually given 4 times per day at evenly spaced intervals during waking hours. Each time you use the medication, you will inhale up to 9 breaths of the medication. Follow your doctor's instructions.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. Most people start treatment with 1 to 3 breaths per treatment session, slowly increasing the number to 9 breaths per session.

Do not use more than 9 breaths per treatment session. Wash your hands before preparing your treprostinil doses in the inhalation system.

One ampule of treprostinil inhalation contains enough medicine for all 4 of a day's doses.

Before your first dose of each day, twist off the top of one ampule and squeeze out the entire contents into the medicine cup of the inhalation system. At the end of the day after the last dose has been given, empty and rinse out the medicine cup, even if there is still unused treprostinil left in it.

To keep the medicine in the cup from spilling, store the inhalation system upright and tightly capped with the plugs when not in use.

The effects of treprostinil inhalation will lessen over time between doses. Talk with your doctor if you need to time your dosing around any planned activities.

Call your doctor if your symptoms do not improve or if they get worse.

It is important to use treprostinil regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. Make sure you have a backup inhalation system available so as not to interrupt your treatment if one system stops working.

Store treprostinil ampules in their foil pouch at room temperature away from moisture, heat, and light. Once you have opened a foil pouch, the ampules in it should be used within 7 days.

Any treprostinil placed into the medicine cup of the inhalation system must be used within 24 hours. Throw away any unused medicine at the end of the day after your last dose.

What happens if I miss a dose?

Call your doctor for instructions.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include flushing (warmth, redness or tingling), headache, nausea, vomiting, diarrhea, feeling light-headed, or fainting.

What should I avoid while using treprostinil inhalation?

Avoid getting treprostinil in your eyes or on your skin. If this does happen, rinse with water. Do not swallow treprostinil inhalation. The medication should be inhaled using only the Tyvaso inhalation system. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Treprostinil inhalation side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• 
  

  new or worsening PAH symptoms such as feeling short of breath (even with mild exertion), tiredness, chest pain, and pale skin;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  fever, chills, cough with yellow or green mucus, stabbing chest pain, wheezing;

  
  


• 
  

  unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;

  
  


• 
  

  pale skin, weakness, easy bruising;

  
  


• 
  

  unexpected vaginal bleeding;

  
  


• 
  

  blood in your urine or stools, black or tarry stools;

  
  


• 
  

  coughing up blood or vomit that looks like coffee grounds; or

  
  


• 
  

  swelling of your ankles or feet.

  
  

Less serious side effects may include:

• 
  

  cough, sore throat;

  
  


• 
  

  pain or irritation in your throat after use;

  
  


• 
  

  dizziness;

  
  


• 
  

  nausea, diarrhea;

  
  


• 
  

  headache or jaw pain; or

  
  


• 
  

  flushing (warmth, redness or tingling).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect treprostinil inhalation?

Before using treprostinil, tell your doctor if you are using any of the following drugs:

• 
  

  gemfibrozil (Lopid);

  
  


• 
  

  delavirdine (Rescriptor);

  
  


• 
  

  nicardipine (Cardene);

  
  


• 
  

  pioglitazone (Actos, ActoPlus Met, Duetact);

  
  


• 
  

  tolbutamide (Orinase);

  
  


• 
  

  an antibiotic such as rifampin (Rifater, Rifadin, Rifamate) or rifapentine (Priftin);

  
  


• 
  

  antifungal medication such as fluconazole (Diflucan), or ketoconazole (Nizoral);

  
  


• 
  

  blood pressure medication;

  
  


• 
  

  a blood thinner such as warfarin (Coumadin).

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  medication to treat congestive heart failure, such as hydralazine (Apresoline, BiDil), nesiritide (Natrecor), nitroglycerin, or nitroprusside (Nitropress);

  
  


• 
  

  an NSAID (non-steroidal anti-inflammatory drug) such as flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), mefenamic acid (Ponstel), or piroxicam (Feldene);

  
  


• 
  

  seizure medication such as carbamazepine (Carbatrol, Tegretol), phenytoin (Dilantin) fosphenytoin (Cerebyx), phenobarbital (Solfoton), primidone (Mysoline), or secobarbital (Seconal);or

  
  


• 
  

  sulfa drugs such as sulfisoxazole (Bactrim, Cotrim, Gantanol, Gantrisin, Septra), and others.

  
  

This list is not complete and there may be other drugs that can interact with treprostinil. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Tyvaso resources

• Tyvaso Side Effects (in more detail)
• Tyvaso Use in Pregnancy & Breastfeeding
• Tyvaso Drug Interactions
• Tyvaso Support Group
• 4 Reviews for Tyvaso - Add your own review/rating

• Tyvaso Prescribing Information (FDA)


• Tyvaso Consumer Overview


• Tyvaso Advanced Consumer (Micromedex) - Includes Dosage Information


• Tyvaso Inhalation Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Treprostinil Professional Patient Advice (Wolters Kluwer)


• Remodulin Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Remodulin Prescribing Information (FDA)


• Remodulin Monograph (AHFS DI)


• Remodulin Advanced Consumer (Micromedex) - Includes Dosage Information

Compare Tyvaso with other medications

• Pulmonary Arterial Hypertension

Where can I get more information?

• Your doctor or pharmacist can provide more information about treprostinil inhalation.

See also: Tyvaso side effects (in more detail)

Iopodic Acid

CAS registry number (Chemical Abstracts Service)

0005587-89-3

Chemical Formula

C12-H13-I3-N2-O2

Molecular Weight

597

Therapeutic Categories

Contrast medium, cholecysto-cholangiography

Diagnostic agent, gall-bladder function

Chemical Name

Benzenepropanoic acid, 3-[[(dimethylamino)methylene]amino]-2,4,6-triiodo-

Foreign Name

• Iopodinsäure (German)

Generic Names

• Iopodinsäure, Natriumsalz (IS)
• SQ 15761 (IS)

Brand Name

• Biloptin
  Schering, Luxembourg

International Drug Name Search

Glossary

IS	Inofficial Synonym

Click for further information on drug naming conventions and International Nonproprietary Names.

Talwin NX

Generic Name: pentazocine and naloxone (Oral route)

nal-OX-one hye-droe-KLOR-ide, pen-TAZ-oh-seen hye-droe-KLOR-ide

Oral route(Tablet)

Pentazocine hydrochloride/naloxone hydrochloride is intended for oral use only. Severe, potentially lethal, reactions may result from misuse of pentazocine/naloxone by injection either alone or in combination with other substances .

Commonly used brand name(s)

In the U.S.

• Talwin NX

Available Dosage Forms:

• Tablet

Therapeutic Class: Analgesic

Pharmacologic Class: Naloxone

Uses For Talwin NX

Pentazocine and naloxone combination is used to relieve moderate to severe pain.

Pentazocine belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.

Naloxone is an opioid antagonist. It acts on the CNS to block the effects of narcotics, especially the "high'' feeling that makes you want to use them. It will not produce any narcotic-like effects or cause mental or physical dependence.

When pentazocine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor's prescription.

Before Using Talwin NX

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of pentazocine and naloxone combination in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pentazocine and naloxone combination in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving pentazocine and naloxone combination.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alfentanil


• Alphaprodine


• Codeine


• Dihydrocodeine


• Fentanyl


• Fospropofol


• Hydrocodone


• Hydromorphone


• Levorphanol


• Meperidine


• Methadone


• Morphine


• Morphine Sulfate Liposome


• Oxycodone


• Oxymorphone


• Propoxyphene


• Selegiline


• Sibutramine


• Sufentanil


• Tapentadol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Clonidine


• Fluoxetine


• Yohimbine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Addison's disease (adrenal gland problem) or


• Alcohol abuse, or history of or


• Asthma, severe or


• Brain tumor, history of or


• Breathing problems, severe (e.g., hypoxia, hypercapnia) or


• Cholecystitis (inflammation of the gallbladder) or


• Chronic obstructive pulmonary disease (COPD) or


• Cor pulmonale (serious heart condition) or


• Drug dependence, especially with narcotics, or history of or


• Enlarged prostate (BPH, prostatic hypertrophy) or


• Gallbladder disease or gallstones or


• Head injuries, history of or


• Hypothyroidism (an underactive thyroid) or


• Intestinal or bowel blockage or


• Kyphoscoliosis (severe curvature of the spine with breathing problems) or


• Mental illness, history of or


• Pancreatitis (inflammation of the pancreas) or


• Problems with passing urine or


• Respiratory depression (very slow breathing) or


• Stomach or digestive problems (e.g., slow or inflamed bowels)—Use with caution. May increase risk for more serious side effects.

• Heart attack, recent or


• Heart or blood vessel disease or


• Hypertension (high blood pressure) or


• Porphyria (an enzyme problem) or


• Seizures, history of—Use with caution. May make these conditions worse.

• Kidney disease or


• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of Talwin NX

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence).

Tell your doctor if you smoke tobacco. Smoking may change how well this medicine works.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablet):
  
  • For moderate to severe pain:
    
    • Adults, teenagers, and children 12 years of age and older—At first, one tablet every 3 or 4 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 12 tablets per day.
    
    
    • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Make sure you store the medicine in a safe and secure place to prevent others from getting it.

Precautions While Using Talwin NX

It is very important that your doctor check the progress of you or your child while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you or your child should continue to take it.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before you or your child take any of the medicines listed above while you are using this medicine.

This medicine may be habit-forming. If you or your child feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

This medicine may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you or your child to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

If you or your child have been using this medicine regularly for several weeks or longer, do not change your dose or suddenly stop using it without checking with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.

Using this medicine while you are pregnant may cause serious unwanted effects in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Talwin NX Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Black, tarry stools


• chest pain


• chills


• cough or hoarseness


• difficult or troubled breathing


• fever


• fever with or without chills


• general feeling of tiredness or weakness


• irregular, fast or slow, or shallow breathing


• lower back or side pain


• painful or difficult urination


• pale or blue lips, fingernails, or skin


• shakiness in the legs, arms, hands, or feet


• shortness of breath


• sore throat


• sores, ulcers, or white spots on the lips or in the mouth


• swollen glands


• trembling or shaking of the hands or feet


• unusual bleeding or bruising


• unusual tiredness or weakness

Incidence not known

• Blistering, peeling, or loosening of the skin


• blurred vision


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• confusion


• decrease in the frequency of urination


• diarrhea


• difficulty in passing urine (dribbling)


• difficulty with swallowing


• dizziness


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• fainting


• fast, slow, pounding, or irregular heartbeat or pulse


• feeling of warmth


• headache


• hives


• itching


• joint or muscle pain


• loss of bladder control


• loss of consciousness


• nervousness


• pounding in the ears


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• rapid breathing


• red skin lesions, often with a purple center


• red, irritated eyes


• redness of the face, neck, arms, and occasionally, upper chest


• skin rash


• sweating


• swelling of the lower legs or arms


• swelling of the face


• tightness in the chest


• total body jerking


• upper abdominal or stomach pain


• weight gain


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Seeing, hearing, or feeling things that are not there


• seizures (convulsions)


• sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

• Abdominal or stomach distress


• hives or welts


• redness of the skin

Incidence not known

• Blistering, crusting, irritation, itching, or reddening of the skin


• confusion about identity, place, and time


• constipation


• constricted, pinpoint, or small pupils (black part of the eye)


• continuing ringing or buzzing or other unexplained noise in the ears


• cracked, dry, or scaly skin


• depression


• difficulty in focusing the eyes


• disturbed dreams


• drowsiness


• dry mouth


• excitement


• false or unusual sense of well-being


• hearing loss


• irritability


• lightheadedness


• loss of appetite


• mood or mental changes


• nausea


• relaxed and calm feeling


• trouble with sleeping


• unable to sleep


• vomiting


• weakness


• weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Talwin NX side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Talwin NX resources

• Talwin NX Side Effects (in more detail)
• Talwin NX Use in Pregnancy & Breastfeeding
• Drug Images
• Talwin NX Drug Interactions
• Talwin NX Support Group
• 8 Reviews for Talwin NX - Add your own review/rating

• Talwin NX Concise Consumer Information (Cerner Multum)


• Talwin Nx MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Talwin NX with other medications

• Pain

Collagenase Ointment

Pronunciation: COL-a-geh-nase
Generic Name: Collagenase
Brand Name: Santyl

Collagenase Ointment is used for:

Removing dead skin from wounds and burned areas.

Collagenase Ointment is an enzymatic debriding ointment. It works by breaking down dead skin.

Do NOT use Collagenase Ointment if:

• you are allergic to any ingredient in Collagenase Ointment

Contact your doctor or health care provider right away if any of these apply to you.

Before using Collagenase Ointment:

Some medical conditions may interact with Collagenase Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you are in very poor health

Some MEDICINES MAY INTERACT with Collagenase Ointment. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Products that contain mercury or silver (eg, certain antiseptics) because they may decrease Collagenase Ointment's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Collagenase Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Collagenase Ointment:

Use Collagenase Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Cleanse the affected area as directed with normal saline or an appropriate cleanser before you apply Collagenase Ointment. Ask your doctor if you have questions about appropriate cleansers.


• If you are also using an antibiotic powder, apply it to the affected area before you apply Collagenase Ointment.


• Follow your doctor's instructions for using Collagenase Ointment. You may be instructed to apply it directly to the wound, or to a sterile gauze pad that will then be applied to the wound. Ask your doctor if you have questions about how to use Collagenase Ointment.


• Do not get Collagenase Ointment on the healthy skin around the affected area.


• If you miss a dose of Collagenase Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Collagenase Ointment.

Important safety information:

• Check with your doctor before you use any other medicines on the affected area. This includes cleansers and soaking solutions. Some of these products may decrease Collagenase Ointments effectiveness.


• Collagenase Ointment should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Collagenase Ointment while you are pregnant. If you are or will be breast-feeding while you use Collagenase Ointment, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Collagenase Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Collagenase Ointment. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); signs of infection (eg, fever, chills, or persistent sore throat).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Collagenase Ointment:

Store Collagenase Ointment below 77 degrees F (25 degrees C). Store away from heat and light. Keep Collagenase Ointment out of the reach of children and away from pets.

General information:

• If you have any questions about Collagenase Ointment, please talk with your doctor, pharmacist, or other health care provider.


• Collagenase Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Collagenase Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Collagenase resources

• Collagenase Use in Pregnancy & Breastfeeding
• Collagenase Drug Interactions
• Collagenase Support Group
• 0 Reviews for Collagenase - Add your own review/rating

Compare Collagenase with other medications

• Actinic Keratosis

Fosamprenavir Suspension

Pronunciation: FOS-am-PREN-a-vir
Generic Name: Fosamprenavir
Brand Name: Lexiva

Fosamprenavir Suspension is used for:

Treating HIV infection in some patients when used in combination with certain other medicines.

Fosamprenavir Suspension is an HIV protease inhibitor. It works by slowing the growth of HIV, the virus that causes AIDS.

Do NOT use Fosamprenavir Suspension if:

• you are allergic to any ingredient in Fosamprenavir Suspension or to amprenavir


• you are taking alfuzosin, amprenavir, astemizole, cisapride, conivaptan, delavirdine, erythromycin, an ergot medicine (eg, ergotamine), pimozide, rifampin, salmeterol, St. John's wort, or terfenadine


• you are taking a hormonal contraceptive (eg, birth control pills), certain benzodiazepines (eg, midazolam, triazolam), or certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin)


• you are taking sildenafil for pulmonary arterial hypertension (PAH)


• you are taking flecainide or propafenone along with ritonavir

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fosamprenavir Suspension:

Some medical conditions may interact with Fosamprenavir Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have had a severe allergic reaction (eg, a severe rash, hives, itching, breathing difficulties, or dizziness) to a sulfonamide medicine such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide


• if you have liver problems, hepatitis, or a history of abnormal liver function tests


• if you have a history of heart problems, high blood pressure, kidney problems, diabetes, bleeding problems (eg, hemophilia), high blood cholesterol or lipid levels, or a skin rash


• if you smoke

Some MEDICINES MAY INTERACT with Fosamprenavir Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Astemizole, cisapride, ergot medicines (eg, ergotamine), erythromycin, pimozide, salmeterol, or terfenadine because serious side effects, such as seizures, blood vessel problems, or heart problems (eg, irregular heartbeat), may occur


• Flecainide or propafenone along with ritonavirbecause serious heart problems (eg, irregular heartbeat) may occur


• Alfuzosin because the risk of severe low blood pressure may be increased


• Certain benzodiazepines (eg, midazolam, triazolam) because serious side effects, such as increased or prolonged sedation or breathing problems, may occur


• Hormonal contraceptives (eg, birth control pills), especially if taken along with ritonavir, because their effectiveness may be decreased and liver problems may occur


• Amprenavir because it may increase the risk of Fosamprenavir Suspension's side effects


• Rifampin or St. John's wort because they may decrease Fosamprenavir Suspension's effectiveness


• Conivaptan, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), ranolazine, or sildenafil (when used for PAH) because the risk of their side effects may be increased by Fosamprenavir Suspension


• Delavirdine because its effectiveness may be decreased by Fosamprenavir Suspension


• Many prescription and nonprescription medicines (eg, used for cancer, infections, asthma, immune suppression, inflammation, aches and pains, gout, high blood pressure, high cholesterol, heart problems, irregular heartbeat, angina, blood clotting problems, mood or mental problems, sinus problems, stomach problems or indigestion, erectile dysfunction, PAH, seizures, sleeping problems, urinary problems, HIV infection), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo) may interact with Fosamprenavir Suspension, increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fosamprenavir Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fosamprenavir Suspension:

Use Fosamprenavir Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Fosamprenavir Suspension. Talk to your pharmacist if you have questions about this information.


• Adults should take Fosamprenavir Suspension by mouth without food.


• Children should take Fosamprenavir Suspension by mouth with food. If vomiting occurs within 30 minutes after taking Fosamprenavir Suspension, the dose should be taken again.


• Shake well before each use.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• You may refrigerate Fosamprenavir Suspension to help improve the taste. Do not freeze.


• If you take an aluminum- or magnesium-containing antacid, ask your doctor or pharmacist how to take it with Fosamprenavir Suspension.


• Do not change your dose or stop taking Fosamprenavir Suspension without talking with your doctor first. Continue to take Fosamprenavir Suspension even if you feel well. Do not miss any doses.


• Taking Fosamprenavir Suspension at the same time(s) each day will help you remember to take it. It is important to not miss any doses of Fosamprenavir Suspension.


• If you miss a dose of Fosamprenavir Suspension, take it as soon as you remember. If you miss a dose of Fosamprenavir Suspension by more than 4 hours, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Fosamprenavir Suspension.

Important safety information:

• Do not take more than the recommended dose without checking with your doctor.


• Fosamprenavir Suspension is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.


• Fosamprenavir Suspension does not stop the spread of HIV to others through blood or sexual contact. Use barrier forms of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.


• When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Fosamprenavir Suspension, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.


• Fosamprenavir Suspension may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice signs or symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Fosamprenavir Suspension.


• Severe and sometimes life-threatening skin reactions have occurred in patients taking Fosamprenavir Suspension. Contact your doctor right away if you develop any type of skin reaction (eg, red, swollen, blistered, or peeling skin).


• Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Fosamprenavir Suspension. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.


• Diabetes patients - Fosamprenavir Suspension may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Fosamprenavir Suspension may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.


• Hormonal birth control (eg, birth control pills) may not work as well while you are using Fosamprenavir Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).


• Lab tests, including liver function, cholesterol or triglyceride levels, white blood cell count, and blood sugar levels, may be performed while you use Fosamprenavir Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Caution is advised when using Fosamprenavir Suspension in CHILDREN; they may be more sensitive to its effects, especially vomiting.


• Fosamprenavir Suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fosamprenavir Suspension while you are pregnant. It is not known if Fosamprenavir Suspension is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Fosamprenavir Suspension to the baby.

Possible side effects of Fosamprenavir Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; nausea; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); loss of appetite; signs of infection (eg, fever, chills, sore throat); swollen, reddened, or blistered skin; symptoms of a heart attack (eg, chest pain; fainting; numbness of an arm or leg; sudden, severe headache or vomiting); symptoms of kidney stones (eg, lower back or side pain, blood in the urine, painful urination); unusual increase in thirst or urination; unusual tiredness or weakness; weight loss; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Fosamprenavir side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Fosamprenavir Suspension:

Store Fosamprenavir Suspension in the refrigerator or at room temperature, between 41 and 86 degrees F (5 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep the container tightly closed. Do not use after the expiration date. Keep Fosamprenavir Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Fosamprenavir Suspension, please talk with your doctor, pharmacist, or other health care provider.


• Fosamprenavir Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Fosamprenavir Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Fosamprenavir resources

• Fosamprenavir Side Effects (in more detail)
• Fosamprenavir Use in Pregnancy & Breastfeeding
• Fosamprenavir Drug Interactions
• Fosamprenavir Support Group
• 0 Reviews for Fosamprenavir - Add your own review/rating

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Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols

Pronunciation: FOE-lik AS-id/VYE-ta-min/oh-MAY-ga 3 AS-ids/fi-to-STER-ols
Generic Name: Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols
Brand Name: Animi-3

Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols is used for:

A dietary supplement. It may also be used for other conditions as determined by your doctor.

Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols is a vitamin, folic acid, omega-3 acid, and phytosterol combination. It works by providing vitamins, folic acid, and essential fatty acids to the body to help meet nutritional requirements.

Do NOT use Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols if:

• you are allergic to any ingredient in Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols

Contact your doctor or health care provider right away if any of these apply to you.

Before using Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols:

Some medical conditions may interact with Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have anemia (eg, pernicious anemia)


• if you are receiving dialysis

Some MEDICINES MAY INTERACT with Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Fluorouracil because the risks of its side effects may be increased by Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols


• Hydantoins (eg, phenytoin) or levodopa because their effectiveness may be decreased by Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols

This may not be a complete list of all interactions that may occur. Ask your health care provider if Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols:

Use Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Take Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols with a full glass of water (8 oz/240 mL).


• If you miss a dose of Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols.

Important safety information:

• Do not take large doses of vitamins (megadoses or megavitamin therapy) while you use Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols unless your doctor tells you to.


• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols has pyridoxine (vitamin B₆), cyanocobalamin (vitamin B₁₂), and folic acid in it. Before you start any new medicine, check the label to see if it has pyridoxine, cyanocobalamin, or folic acid in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols.


• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols while you are pregnant. It is not known if Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols is found in breast milk. If you are or will be breast-feeding while you use Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols:

All medicines may cause side effects, but many people have no, or minor side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); feeling of swelling of the entire body; numbness or tingling of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols:

Store Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols out of the reach of children and away from pets.

General information:

• If you have any questions about Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols, please talk with your doctor, pharmacist, or other health care provider.


• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols resources

• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols Side Effects (in more detail)
• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols Use in Pregnancy & Breastfeeding
• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols Drug Interactions
• Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols Support Group
• 13 Reviews for Folic Acid/Vitamin B6/Vitamin B12/Omega-3 Acids/Phytosterols - Add your own review/rating

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• ADHD
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